Regular gutter cleaning is essential if you want to prevent any damage to your gutters and building. If your gutters are not clean the flow of rainwater will be very poor which will result in a build-up of dirt in them and it might result in birds nesting and various bacteria and worms living in your gutters.
Very often the moss that builds up on your roof also falls into your gutters which too can be unhealthy for your gutters. If you live in an area with trees nearby we would recommend having your gutters cleaned at least once a year.